GERD / Acid reflux
Heartburn
Peptic (gastric & duodenal) ulcers
H. pylori–associated ulcers (used with antibiotics)
Erosive esophagitis
Preventing ulcers in patients taking NSAIDs long-term
Zollinger–Ellison syndrome (excess acid production)
Chronic gastritis and dyspepsia
Contraindications:
Avoid use in:
Known allergy to Esomeprazole, omeprazole, or other PPIs
Severe liver disease (dose adjustment needed)
Combination with certain drugs (risk of interactions):
Clopidogrel (reduces its effect)
Nelfinavir (antiviral)
Rilpivirine, warfarin (needs caution)
Side Effects:
Common
Headache
Nausea, vomiting
Diarrhea or constipation
Gas / bloating
Stomach discomfort
Dry mouth
Dizziness
Less common
Joint or muscle pain
Vitamin B12 deficiency (long-term use)
Low magnesium (prolonged use)
Precautions:
Take on an empty stomach, 30 minutes before breakfast.
Do not crush or chew the tablet.
Long-term use (>3–6 months) should be monitored due to risk of:
Vitamin B12 deficiency
Low magnesium
Calcium deficiency
Use cautiously in kidney disease
Avoid in patients on clopidogrel unless advised
Pregnant or breastfeeding women should consult a doctor.
Dietary Restrictions:
Avoid / Limit
Spicy, oily, fried foods
Excess tea/coffee
Citrus fruits if they worsen symptoms
Tomato-based foods
Sodas and carbonated drinks
Alcohol
Chocolate
Late-night meals
Recommended
Eat small, frequent meals
Avoid lying down 2–3 hours after meals
Maintain healthy weight
Drink plenty of water
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