Used For:

• Treatment of heart failure with reduced ejection fraction (HFrEF), resistant hypertension, primary hyperaldosteronism, edema secondary to cirrhosis, edema secondary to a nephrotic syndrome that is not adequately controlled using alternative therapies, and hypokalemia

Adult Dosage:

• 1) 50 mg daily for HFrEF 2) 100 mg daily for resistant hypertension 3) 400 mg daily for edema due to cirrhosis or 200mg daily for edema due to nephrotic syndrome 4) 400 mg daily for primary hyperaldosteronism 5) 200 mg daily for diuretic-induced hypokalemia 6) 200 mg daily for hirsutism 7) 200 mg daily for acne vulgaris.

Pack:

• 15 s

Contraindications:

• Hyperkalemia and in those at increased risk of developing hyperkalemia; renal impairment.

Side Effects:

• Men specifically may experience gynecomastia, loss of libido, and general feminization.women can experience menstrual irregularities

Precautions:

• Hyperkalemia can be due to spironolactone alone or a synergistic side effect from multiple medications such as beta-blockers, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers that clinicians often prescribe to patients for indications such as hypertension or heart failure.

Dietary Restrictions:

• Avoid foods and supplements high in potassium, such as bananas, avocados, salt substitutes, and dried fruits,