Used For:

• Treatment of heart failure with reduced ejection fraction (HFrEF), resistant hypertension, primary hyperaldosteronism, edema secondary to cirrhosis, edema secondary to a nephrotic syndrome that is not adequately controlled using alternative therapies, and hypokalemia

Contraindications:

• Hyperkalemia and in those at increased risk of developing hyperkalemia; renal impairment.

Side Effects:

• Men specifically may experience gynecomastia, loss of libido, and general feminization.women can experience menstrual irregularities

Precautions:

• Hyperkalemia can be due to spironolactone alone or a synergistic side effect from multiple medications such as beta-blockers, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers that clinicians often prescribe to patients for indications such as hypertension or heart failure.

Dietary Restrictions:

• Avoid foods and supplements high in potassium, such as bananas, avocados, salt substitutes, and dried fruits,