Used For:

• HIV treatment

Contraindications:

• Do NOT use Abavir if:Known hypersensitivity to abacavirHLA-B*57:01 positive (genetic test mandatory before starting)Previous abacavir hypersensitivity reaction (never re-challenge — can be fatal)Severe liver impairment

Side Effects:

• Common Side EffectsNausea, vomitingHeadacheFatigueFeverDiarrheaInsomniaSerious (Rare) Side EffectsHypersensitivity reaction (most serious)Lactic acidosisHepatomegaly with steatosisIncreased risk of cardiovascular events (controversial but noted)Liver enzyme elevation

Precautions:

• PrecautionsHLA-B*57:01 testing is mandatory before starting therapyUse cautiously in:Patients with cardiovascular diseaseLiver disease (including hepatitis B or C)Never stop or change ART regimen without medical supervisionPatients should carry an Abacavir Alert CardStrict adherence required to prevent resistance

Dietary Restrictions:

• Can be taken with or without foodAvoid alcohol (↑ liver toxicity risk)Maintain a balanced, nutritious diet to support immune healthAvoid herbal supplements without medical advice (drug interactions possible)